2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- (9CI) - Names and Identifiers
2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- (9CI) - Physico-chemical Properties
Molecular Formula | C18H29NO2
|
Molar Mass | 291.42836 |
Melting Point | 55-75°C |
Solubility | Acetone (Slightly), Chloroform (Slightly), Methanol |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | Refrigerator |
2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- (9CI) - Introduction
rac Penbutolol (vagal amine inhibitor-pivalon) is a beta-blocker with non-selective effects, consisting of two mirror image isomers. Its main features are as follows:
1. Nature: it is a white crystalline powder, insoluble in water, soluble in alcohol and organic solvents.
2. Use: rac Penbutolol is mainly used for the treatment of hypertension and arrhythmia. It reduces cardiac contractility and heart rate by inhibiting the activity of beta receptors, thereby reducing blood pressure and the onset of arrhythmias.
3. Preparation method: the synthesis method of rac Penbutolol includes synthesizing imine by corresponding aldehyde condensation, and obtaining by further reduction and separation. The detailed production method can be achieved by a chemical synthesis method.
4. Safety Information: rac Penbutolol has high safety in clinical use, but there are still some side effects, such as dizziness, fatigue, palpitations, hypotension and hypoglycemia. These side effects can be mitigated by adjusting the dosage according to individual conditions.
It should be noted that the above information is for reference only. The specific use should follow the doctor's advice and strictly follow the medication instructions in the drug instructions.
Last Update:2024-04-09 15:18:07